Physiology and Metabolism of 'Neisseria gonorrhoeae'.

Abstract

Studies which have examined various aspects of the physiology and metabolism of Neisseria gonorrhoeae are reported. The principal findings are: (1) Glucose is dissimilated by a combination of the Entner-Doudoroff and pentose phosphate pathways. (2) The dissimilation of glucose is an aerobic process; no growth occurs under anaerobic conditions. (3) Growth temperature markedly affects the dissimilation of glucose. (4) Glucose-limited cultures are susceptible to autolysis; nitrogen limited cultures are not. (5) Glucosamine enhances autolysis in glucose-depleted cultures. (6) N. gonorrhoeae and N. meningitidis are susceptible to growth inhibition by the gonadal steroid progesterone. The site of inhibition appears to be located in the cytoplasmic membrane.

Document Details

Document Type
Technical Report
Publication Date
Dec 01, 1974
Accession Number
ADA003334

Entities

People

  • Stephen A. Morse

Organizations

  • Harvard T.H. Chan School of Public Health

Tags

DTIC Thesaurus Topics

  • Aerobic Processes
  • Anatomy
  • Biological Sciences
  • Breakpoint Temperature
  • Cell Membrane
  • Death
  • Inhibition
  • Membranes
  • Metabolism
  • Nitrogen
  • Physiology
  • Progesterone

Fields of Study

  • Biology

Readers

  • Aquatic Ecology
  • Microbial Pathology
  • Molecular and Cellular Biochemistry