Development of a Synthetic Polymer Burn Covering.
Abstract
The quantitative in vivo evaluation of a collagen/poly-epsilon-caprolactone laminate burn covering with human cadaver skin as a reference has been carried out using the burned rat model. Insensible water loss and adherence of the covering to the excised wound have been measured. Three thicknesses (0.0005, 0.001, 0.003 inch) of poly-epsilon-caprolactone (PCL) laminated to collagen film (0.001-0.002 inch) were evaluated. The covering is grafted with the collagen towards the wound. The authors conclude that the collagen/PCL laminate, can significantly reduce and control insensible water loss from a wound. However, early adherence to wound is lacking. Therefore further development of the collagen surface is required.
Document Details
- Document Type
- Technical Report
- Publication Date
- Dec 31, 1974
- Accession Number
- ADA003612
Entities
People
- A. D. Schwope
- D. L. Wise