Effects of Excessive Amounts of Implanted Resorbable Calcium Aluminate Ceramics on Some Physiological and Histological Parameters in Rats.
Abstract
Experiments were designed to investigate whether implanting of excessive masses of porous resorbable calcium aluminate ceramic for different durations 75, 150, and 300 days of time would cause any physiological and/or histopathological changes. Radiographs indicated complete compatibility between bone and the implants. Alkaline phosphatase activity implanted with 0.32 grams of ceramic was significantly higher than in sham operated animals. Data from analysis of serum, urine, bone and ceramic indicated that remodeling favored bone formation in animals sacrificed at 75 days and bone resorption in animals sacrificed at 300 days with maximum bone formation at 150 days. Deposition of both calcium and phosphate in the ceramics suggest formation of new bone in the implanted ceramics.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jan 01, 1974
- Accession Number
- ADA004176
Entities
People
- Blanche Antonieta Perpetua Carvalho
Organizations
- University of Dayton Research Institute