An EEG Study of Morphine Tolerance in the Rat

Abstract

Tolerance, manifested by a diminished EEG response at cortical and subcortical recording sites, was found in rats subjected to repeated systemic injections of morphine sulfate. Reversal of tolerance to morphine resulted from destruction of the medial thalamus.

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Document Details

Document Type
Technical Report
Publication Date
Aug 01, 1974
Accession Number
ADA004195

Entities

People

  • George N. Catravas
  • H. Teitelbaum
  • W. L. Mcfarland

Organizations

  • Armed Forces Radiobiology Research Institute

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Ablation
  • Abstracts
  • Alkenes
  • Base Lines
  • Brain
  • Central Nervous System
  • Cerebellum
  • Cerebral Cortex
  • Cerebrum
  • Hippocampus
  • Hypothalamus
  • Laboratory Animals
  • Nervous System
  • Neurosciences
  • Sensitivity
  • Thalamus

Fields of Study

  • Biology
  • Psychology

Readers

  • Neuroscience
  • Neurotrauma and Rehabilitation Medicine.