A New Technique for Evaluating Antigenic Relatedness Among Viruses

Abstract

The major objectives of the work were to evaluate the effectiveness of the macrophage migration inhibition (MMI) test for: (a) differentiating between closely related viruses that cross-react in the standard serological tests available and (b) rapid identification of a viral agent in a diagnostic context. Essentially, objective (a) was realized but objective (b) was not. The MMI test was found to be an effective means of differentiating two serologically cross-reacting strains of infectious bronchitis virus, an avian coronavirus, two nuclear polyhedrosis viruses which are being investigated for possible use in the biological control of insects, and Adenovirus types 1, 4, 5, and 7.

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Document Details

Document Type
Technical Report
Publication Date
Jan 29, 1975
Accession Number
ADA004664

Entities

People

  • Frank M. Hetrick

Organizations

  • University of Maryland

Tags

DTIC Thesaurus Topics

  • Adenoviruses
  • Animals
  • Antigens
  • Baculoviridae
  • Cells
  • Cellular Structures
  • Inhibition
  • Insect Viruses
  • Lepidoptera
  • Lymphatic System
  • Macrophages
  • Microbiology
  • Migration
  • Military Research
  • Proteins
  • Rodents
  • Viruses

Fields of Study

  • Biology

Readers

  • Gulf War Illness and Chronic Multisymptom Illness in Veterans.
  • Software Engineering
  • Virology (or Medical Virology).