Hazard Evaluation of Candidate Face Net Impregnant Ent-20831 Bis(1-Methylbutyl) Malate Study.

Abstract

A hazard evaluation of the candidate face net impregnant, bis(1-methylbutyl) malate (ENT-20831), was performed by means of laboratory animal studies using rats and rabbits. The technical grade compound did not produce primary irritation when applied to the intact or abraded skin of rabbits. No corneal injury, iritis or conjunctivitis was observed after a single application of the technical grade compound to the eyes of rabbits. Data indicate little acute toxic hazard from accidential ingestion. Acute aerosol and subchronic saturated vapor inhalation exposures of rats resulted experimentally in no deleterious effect. It is recommended that ENT-20831 be approved for testing as a candidate face net impregnant.

Document Details

Document Type
Technical Report
Publication Date
Aug 01, 1974
Accession Number
ADA005028

Entities

People

  • Conrad R. Pope
  • Joseph A. Macko Jr.
  • Maurice H. Weeks

Organizations

  • United States Army Medical Command

Tags

DTIC Thesaurus Topics

  • Animals
  • Conjunctival Diseases
  • Digestive System Processes
  • Eye Diseases
  • Hazards
  • Impregnation
  • Irritation
  • Laboratory Animals
  • Test And Evaluation
  • Toxic Hazards

Readers

  • Toxicology/Environmental Toxicology