Hazard Evaluation of Candidate Face Net Impregnant ENT-4841-Gc, 2-(2-Butoxyethoxy)-N-Cyclohexylacetamide.
Abstract
A hazard evaluation of the candidate face net impregnant 2-(2-butoxyethoxy)-N-cyclohexylacetamide (ENT-4841-Gc) was performed by means of laboratory animal studies using rats and rabbits. The technical grade compound produced mild primary irritation when applied to the intact or abraded skin of rabbits. Mild injury to the cornea and, in addition, some injury to the conjunctive was observed after a single application of the technical grade compound to the eyes of rabbits. Data indicate little acute toxic hazard from accidental ingestion. Acute aerosol and acute and subchronic saturated vapor inhalation exposures of rats at 24C resulted experimentally in no deleterious effect. Acute saturated vapor exposure with the compound held at 100C caused a reduced body weight gain and lung changes in exposed rats. It is recommended that ENT-4841-Gc not be approved for testing as a candidate face net impregnant.
Document Details
- Document Type
- Technical Report
- Publication Date
- Aug 01, 1974
- Accession Number
- ADA005179
Entities
People
- Conrad R. Pope
- Maurice H. Weeks
Organizations
- United States Army Medical Command