1,2,4-Benzotriazine 1-Oxides as Antifolate-Antimalarials.
Abstract
This work was directed towards the preparation of 3-amino-7-substituted phenylsulfonyl-1,2,4-benzotriazine 1-oxides; a general route to this series was found. Two other desired series of compounds, 3-amino-7-substituted phenylthio-1,2,4-benzotriazine 1-oxides and 3-amino-7-substituted benzylamino-1,2,4-benzotriazine 1-oxides were not prepared, however, the reactions involved in their attempted preparation is summarized.
Document Details
- Document Type
- Technical Report
- Publication Date
- Oct 01, 1974
- Accession Number
- ADA006215
Entities
People
- W. Wesley Parish
- William D. Johnston