Solid State Biology, Cellular Water Structure, and Ion Complexing with Application to Navy Medicine.

Abstract

A comprehensive study of potassium (39K) in normal muscle and brain and other tissues by pulsed nuclear magnetic resonance (NMR) shows relaxation times (T1 and T2) much shorter than in free solution, approaching the short values seen for potassium complexed by ion exchange resins. This evidence suggests that potassium ion in cells is associated with machromolecules and is not in free solution. For all normal tissues, except intestine, potassium T1 NMR decays were simple exponential functions of time, which yielded straight line semilog plots. For six types of animal cancers and for intestine, complex oscillatory patterns of T1 decay were observed. These NMR spin signatures may be useful for the electronic diagnosis of cancer in surgical biopsy specimens, both for the presence of cancer and for the type of cancer. Solid state physical analyses of biological systems suggest that high electric fields may enhance superconductive processes in nerve, and that infrared waves may transmit energy within the lipid bilayer walls of nerves and mitochondria.

Document Details

Document Type
Technical Report
Publication Date
Jan 01, 1975
Accession Number
ADA006469

Entities

People

  • Freeman W. Cope

Organizations

  • Naval Air Warfare Center Warminster

Tags

Communities of Interest

  • Materials and Manufacturing Processes

DTIC Thesaurus Topics

  • Electric Fields
  • Exponential Functions
  • Intestines
  • Ion Exchange
  • Ion Exchange Resins
  • Magnetic Resonance
  • Membrane Lipids
  • Nuclear Magnetic Resonance
  • Potassium
  • Quantum Properties
  • Relaxation Time
  • Resonance
  • Systems Biology

Readers

  • Atmospheric Science / Meteorology, specifically Wind Wave Turbulence.
  • Oncology and Biomarker-Based Cancer Detection.
  • Organic Chemistry

Technology Areas

  • Microelectronics