Annual Research Report 1 July 1973 -- 30 June 1974

Abstract

The objective of this research was to measure and determine the physiological and metabolic pathways of cyclotrimethylenetrinitramine (RDX) following oral, intraperitoneal and intravenous administration; its toxic and resultant pathological effects on the various organ systems; and the development of proper therapeutic and prophylactic procedures.Contents: Pathophysiological studies of potentially toxic substances; Biological effects of electromagnetic pulses; Suppression of secondary disease by in vitro exposure of mixtures of lymphoid and stem cells to purified antilymphocyte antibody; Endotoxin effects of mouse liver adenyl cyclase; Development of clinical approaches for the treatment of radiation sickness and graft versus host disease through management of the intestinal flora; Control of white cell population in the postirradiated animal; Glycoproteins in diabetes; Technetium-99m pyrophosphate--Comparison of ED50 for tetany and acidosis with acute LD50.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Jun 30, 1974
Accession Number
ADA009327

Entities

People

  • C. L. Cloud
  • G. David Ledney
  • M. P. Fink
  • N. R. Schneider
  • W. D. Skidmore
  • W. J. Flor

Organizations

  • Armed Forces Radiobiology Research Institute

Tags

DTIC Thesaurus Topics

  • Arteries
  • Cells
  • Chemical Synthesis
  • Chemistry
  • Health Services
  • Medical Personnel

Fields of Study

  • Medicine

Readers

  • Immunology
  • Molecular and Cellular Biology
  • Toxicology/Environmental Toxicology

Technology Areas

  • Biotechnology
  • Biotechnology - Cancer Biotech