Hazard Evaluation of Candidate Face Net Impregnant ENT-337 DI-Dibutyl Malate.

Abstract

A hazard evaluation of the candidate face net impregnant dl-dibutyl malate (ENT-337) was performed by means of laboratory animal studies using rats and rabbits. The technical grade compound did not produce primary irritation when applied to the intact or abraded skin of rabbits. Mild injury to the cornea and slight chemosis, redness and discharge of the conjunctiva resulted from single application to the eyes of rabbits. Data indicated little toxic hazard from accidental ingestion. Acute aerosol and subchronic saturated vapor inhalation exposures of rats resulted experimentally in no deleterious effect.

Document Details

Document Type
Technical Report
Publication Date
Nov 01, 1974
Accession Number
ADA010337

Entities

People

  • Joseph A. Macko Jr.
  • Maurice H. Weeks

Organizations

  • United States Army Medical Command

Tags

DTIC Thesaurus Topics

  • Animals
  • Biological Sciences
  • Digestive System Processes
  • Eye
  • Hazards
  • Impregnation
  • Irritation
  • Laboratory Animals
  • Test And Evaluation
  • Toxic Hazards

Readers

  • Toxicology/Environmental Toxicology