The Effects of Traumatic Injury on Spinal Cord Blood Flow

Abstract

Using the hydrogen clearance technique, the effect of direct crush injury on blood flow was measured in the lateral white matter and central gray matter of the spinal cord of the adult rhesus monkey. Three measurements were made: at the site of injury (T8-T10), 1 cm above and 1 cm below. After injury, blood flow in the central gray matter declined markedly. However, flow in the lateral funiculus increased 100 percent or more within 2 hours after injury, and then returned to normal range by 8 hours where it remained for at least 24 hours. These data contradict the prevailing theory of a progressive ischemia in the lateral white matter secondary to the development of a hemorrhagic infarct in the central gray matter as a mechanism in crush injury of the cord.

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Document Details

Document Type
Technical Report
Publication Date
Dec 01, 1974
Accession Number
ADA010819

Entities

People

  • A. I. Kobrine
  • A. N. Martins
  • T. F. Doyle

Organizations

  • Armed Forces Radiobiology Research Institute

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Abstracts
  • Animals
  • Arteries
  • Blood
  • Blood Flow
  • Cardiovascular Physiological Phenomena
  • Clearances
  • Ischemia
  • Laboratory Animals
  • Materials
  • Measurement
  • Monkeys
  • Paralysis
  • Rhesus Monkeys
  • Spinal Cord
  • Spinal Injuries
  • Tissues

Readers

  • Cardiovascular Physiology
  • Neurotrauma and Rehabilitation Medicine.
  • Theoretical Analysis.