A Review of the Toxicology of Halogenated Fire Extinguishing Agents

Abstract

Bromotrifluoromethane (Halon 1301), bromochlorodifluoromethane (Halon 1211), and chlorobromomethane (Halon 1011) were evaluated for toxicity and toxic hazards. The most important toxicological effects of these compounds are on the central nervous and cardiovascular systems. The neurological effects are manifested as alterations of perception and a reduction in reaction time and the ability to concentrate on complex intellectual tasks. The cardiovascular effects are manifested as changes in cardiovascular dynamics and the electrical activity of the heart. Clinically important central nervous system effects generally appear at lower levels of exposure than clinically important cardiovascular effects. Behavioral changes and performance decrements during exposure would undoubtedly have some effect on the interaction of the subject with his environment, and such consequences of exposure could be life- threatening.

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Document Details

Document Type
Technical Report
Publication Date
Nov 01, 1974
Accession Number
ADA011538

Entities

People

  • E. W. Van Stee

Organizations

  • Air Force Research Laboratory

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Arteries
  • Blood
  • Cardiac Arrhythmias
  • Cardiovascular Diseases
  • Cardiovascular Physiological Phenomena
  • Cardiovascular System
  • Chemical Synthesis
  • Chemistry
  • Health Services
  • Heart
  • Medical Personnel
  • Pharmacology

Readers

  • Brain and Cognitive Science; Experimental Psychology; Cognitive Neuroscience
  • Cardiovascular Physiology
  • Fire Suppression Systems Design.