Cardiac Sensitization Studies in Dogs with Myocardial Infarctions.

Abstract

In man, myocardial infarction is the most serious form of ischemic cardiovascular disease and, because of its frequent occurrence, it is the single most important type of heart disease. Since myocardial infarction is common in the human population, the authors attempted to determine whether such a condition might place an individual, exposed to high halocarbon concentrations, at greater risk from an epinephrine-induced cardiac arrhythmia. Such exposure conditions could occur in the chemical industry, or in the refrigeration and aerosol industries. Using the dog as an animal model for myocardial infarction, results imply that such an individual, having recovered from myocardial infarction and able to return to work, may be at no greater risk from cardiac sensitization than the normal healthy individual.

Document Details

Document Type
Technical Report
Publication Date
Dec 01, 1974
Accession Number
ADA011859

Entities

People

  • A. Azar
  • B. W. Karrh
  • C. F. Reinhardt
  • H. J. Trochimowicz
  • L. S. Mullin

Organizations

  • Air Force Research Laboratory

Tags

DTIC Thesaurus Topics

  • Arrhythmia
  • Cardiovascular Diseases
  • Chemical Industry
  • Cooperation
  • Diseases And Disorders
  • Epinephrine
  • Heart Diseases
  • Human Population
  • Myocardial Ischemia

Fields of Study

  • Biology

Readers

  • Cardiovascular Physiology
  • Toxicology/Environmental Toxicology