Aerosol Particle Size as a Factor in Pulmonary Toxicity
Abstract
The particle size distribution of inhaled aerosols is a factor in pulmonary toxicity for several reasons. Among those discussed are the relationship between particle size and amount of toxic agent per particle, the influence of aerodynamic and real size on the regional deposition within various anatomical regions of the respiratory tract and the effect of both deposition site and particle size per se on clearance kinetics. The role of particle size in the assessment of environmental hazards is one that is increasingly being realized as important.
Document Details
- Document Type
- Technical Report
- Publication Date
- Dec 01, 1974
- Accession Number
- ADA011872
Entities
People
- O. G. Raabe
- R. F. Phalen
Organizations
- Air Force Research Laboratory