Stress Biophysics.

Abstract

A fully compensated spectrophotofluorimeter, built by the University of Nottingham, England under ONR contract in 1969, was configured to accommodate biological specimens at liquid nitrogen and helium temperatures. The reliability and reproducibility of data obtained due to compensation of all adverse variables in the instrument was assessed. Preliminary information was obtained on the nature of the electron excited state (phosphorescence) in certain molecular domains of connective tissues. The system of measurement was adapted to quantifying the two main molecules of tendon, namely, collagen and proteoglycan simultaneously without chemical disruption. The effort lead to development of a method for assessing the effects of aging and nutrition on the molecular nature of connective tissues.

Document Details

Document Type
Technical Report
Publication Date
Jun 15, 1975
Accession Number
ADA011920

Entities

People

  • Kirk C. Hoerman

Organizations

  • American Dental Association

Tags

DTIC Thesaurus Topics

  • Biological Sciences
  • Biophysics
  • Biospecimens
  • Collagen
  • Compensation
  • Connective Tissue
  • Contracts
  • Electrons
  • Measurement
  • Molecules
  • Nitrogen
  • Nutrition
  • Phosphorescence
  • Polysaccharides
  • Reliability
  • Reproducibility
  • Tissues

Readers

  • Molecular Photonics/Laser Physics
  • Molecular and Cellular Biochemistry
  • Technical Research and Report Writing.

Technology Areas

  • Biotechnology
  • Microelectronics