Initial Slope Index of Total Cerebral Blood Flow Measured by Hydrogen Clearance: A Pragmatic Evaluation

Abstract

An initial slope index of total cerebral blood flow, measured by hydrogen clearance from torcular blood, shows high correlation with flows calculated by bicompartmental analysis. In 247 flow measurements done on 41 rhesus monkeys, a linear regression analysis between these two methods of calculating flow shows a correlation coefficient of 0.9280 with a standard error about y values of plus or minus 7.63. The initial slope index is not only faster to calculate but does not require that a steady state be maintained for 10 minutes.

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Document Details

Document Type
Technical Report
Publication Date
Jun 01, 1975
Accession Number
ADA012864

Entities

People

  • A. I. Kobrine
  • A. N. Martins
  • T. F. Doyle

Organizations

  • Armed Forces Radiobiology Research Institute

Tags

DTIC Thesaurus Topics

  • Abstracts
  • Animals
  • Base Lines
  • Blood
  • Blood Flow
  • Clearances
  • Coefficients
  • Computer Programming
  • Computers
  • Data Analysis
  • Electrodes
  • Hydrogen
  • Information Science
  • Linear Regression Analysis
  • Regression Analysis
  • Skull
  • Steady State

Fields of Study

  • Medicine

Readers

  • Cardiovascular Physiology
  • Combustion and Flow Dynamics.
  • Regression Analysis.