Chemical Comparison of the Polysaccharide Portions of Shigella Lipopolysaccharides and Their Relation to Virulence.
Abstract
The fatty acid content of the lipid A from virulent and avirulent strains of Shigella flexneri 2a was compared and found to be identical in both strains. Using the avirulent S. flexneri 2a strain as a model, data presented here show that the O-side chains of this strain contain an average of 5.8 O-repeat units per side chain if the organism is grown in brain-heart infusion (BHI) broth at several growth rates. However, earlier evidence indicated that cells grown on BHI agar have side chains nearly five times as long. Lipopolysaccharides (LPS) analyses of LPS components from two strains of Neisseria gonorrhoeae and two Shigella-Salmonella hybrids are also presented.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jun 30, 1975
- Accession Number
- ADA013393
Entities
People
- Donald E. Koeltzow
Organizations
- Luther College