Synthesis of Antimalarial C-Nucleosides.

Abstract

Approximately 80 compounds have been submitted to WRAIR for screening against malaria. The compounds synthesized include C-analogs of the antibiotics cordycepin, puromycin and Ara-A as well as C-analogs of adenosine and its derivative. The compounds screened by the Schizonticidal test using ICR/HA Swiss mice were inactive.

Document Details

Document Type
Technical Report
Publication Date
Jan 31, 1975
Accession Number
ADA014271

Entities

People

  • Hassan S. El Khadem

Organizations

  • Michigan Technological University

Tags

DTIC Thesaurus Topics

  • Adenosine
  • Anti-Bacterial Agents
  • Anti-Infective Agents
  • Antimalarials
  • Arthropod Borne Diseases
  • Bacterial Infections And Mycoses
  • Diseases And Disorders
  • Infectious Diseases
  • Malaria
  • Mosquito Borne Diseases
  • Nucleosides
  • Parasitic Diseases
  • Pharmacologic Actions
  • Protozoan Infections

Fields of Study

  • Chemistry

Readers

  • Parasitology and Pharmacology of Malaria.