Hazard Evaluation of Candidate Face Net Impregnant ENT-20127, Pentyl Mandelate.

Abstract

A hazard evaluation of the candidate face net impregnant technical grade pentyl mandelate (ENT 201127) was performed by means of laboratory animal studies using rats, rabbits, and guinea pigs. The technical grade compound did not produce primary irritation when applied to the intact or abraded skin of rabbits. No corneal injury, iritis or conjunctivitis was observed after a single application of the technical grade compound to the eyes of rabbits. Data indicate little acute toxic hazard from accidental ingestion. ENT-20127 did not produce skin sensitivization in guinea pigs. Acute aerosol as well as acute and subchronic saturated vapor inhalation exposures of rats resulted experimentally in no deleterious effect.

Document Details

Document Type
Technical Report
Publication Date
Oct 23, 1975
Accession Number
ADA016920

Entities

People

  • Conrad R. Pope
  • Joseph A. Macko Jr.
  • Maurice H. Weeks

Organizations

  • United States Army Medical Command

Tags

DTIC Thesaurus Topics

  • Anatomy
  • Animals
  • Biological Sciences
  • Cells (Biology)
  • Conjunctival Diseases
  • Digestive System Processes
  • Eukaryotes
  • Eye Diseases
  • Hazards
  • Impregnation
  • Irritation
  • Laboratory Animals
  • Lagomorphs
  • Rodents
  • Test And Evaluation
  • Toxic Hazards

Readers

  • Toxicology/Environmental Toxicology