Genetics of Novel Hybrid Bacteriophage and Development of Generalized Transducing System for 'Salmonella typhosa'.

Abstract

Various hybrid phages between coliphage and Salmonella phage were isolated using bacterial hybrids between E. coli and Salmonella typhimurium. These hybrid phage species were genetically mapped for homology with their parental phages. The role of various parental phage genes of hybrid phages for their replication in S. typhimurium, E. coli-S. typhosa hybrid and E. coli was carefully analyzed. Essential bacterial and viral functions for replication of the hybrid phages in these bacterial strains provided important information for the process of viral infection. The P22-lamda hybrids have capabilities for antigen conversion and generalized transduction in both S. typhimurium and E. coli-S. typhimurium hybrid.

Document Details

Document Type
Technical Report
Publication Date
Dec 29, 1975
Accession Number
ADA018967

Entities

People

  • Nobuto Yamamoto

Organizations

  • Temple University

Tags

DTIC Thesaurus Topics

  • Bacteriophages
  • Biological Sciences
  • Biology
  • Coliphages
  • Conversion
  • Genetics
  • Infection
  • Microbial Genetics
  • Microorganisms
  • Salmonella Phages
  • Wound Infections

Fields of Study

  • Biology

Readers

  • Microbial Pathology

Technology Areas

  • Biotechnology