Measurement of Antifolate Drugs by Microbiological Assay.
Abstract
;Contents: Interim report no. 10 -- Measurement of antifolate drug levels by microbiological assay. Plasma levels of 4,6-diamino-1-(2,4,5-trichloro-phenoxypropyloxy)- 1,2-dihydro-2,2-dimethyl-s-triazine WR-99,210; Interim report no. 11 -- Measurement of antifolate drugs by microbiological assay. Plasma levels of 2,4-diamino-6-(2-naphthyl)-sulfonylquinazoline (WR-158,122) in 11 human subjects given combinations of WR-158,122 and sulfadiazine. Interim report no. 12 -- Measurement of antifolate drugs by microbiological assay. Plasma levels of 1-(2-4,5-trichlorophenoxy-propyloxy)-1,2-dihydro-2,2-dimethyl-s-triazine (WR-99,210) in 8 human subjects given single oral doses of 50 or 250 mg.
Document Details
- Document Type
- Technical Report
- Publication Date
- Dec 15, 1975
- Accession Number
- ADA018992
Entities
People
- Carl C. Smith
- Clara S. Genther
Organizations
- University of Cincinnati