Body Fluid Distribution in Acute Hypercapnia

Abstract

Guinea pigs and rats were exposed to 1.9, 6.9 and 10.8% CO2 for a period of one hour. Measurements of total body water (TBW), extracellular fluid (ECF) and intracellular fluid (ICF) were made using tritiated water and radioactive chloride (Cl36). Control values for TBW, ECF and ICF were 64.6, 28.5 and 36.1 for rats and 61.7, 30.6 and 31.1 for guinea pigs. These values did not change significantly under hypercapin. These results indicate that although no measurable changes occurred in body fluid distribution under hypercapnia, the differences in body water distribution between guinea pigs and rats may help explain species differences in response to hypercapnic stress.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Jun 16, 1975
Accession Number
ADA019922

Entities

People

  • F. T. Abbott
  • Karl E. Schaefer
  • R. D. Murray

Organizations

  • Naval Submarine Medical Research Laboratory

Tags

DTIC Thesaurus Topics

  • Animals
  • Biomedical Research
  • Blood
  • Body Fluids
  • Body Water
  • Body Weight
  • Cells
  • Cellular Structures
  • Fluids
  • Intracellular Fluid
  • Intracellular Space
  • Medical Personnel
  • Navy
  • New England
  • Rodents
  • Submarines
  • Water

Fields of Study

  • Medicine

Readers

  • Cardiovascular Physiology
  • Exercise and Sports Science.