Biochemical Changes in Naval Aircrewmen Caused by Stress in Flight Performance.

Abstract

The pilot study indicates that the excretion of o-hydroxy hippuric acid in urine is a useful addendum to the molecular determinants of stress and, under controlled conditions, may aid in identifying candidates who can or cannot succeed as test parachutists. In concurrent experiments all parachutists studied showed a significant increase in plasma phosphatidyl glycerol, a sensitive and proven indicator for stress. Further studies have shown that the distribution of cyclic AMP in living tissues is ubiquitous and that increased tissue levels are associated with beta adrenergic reactions. It was postulated that changes in tissue cyclic AMP levels might be correlated with physiological changes resulting from the application of whole body stresses, and that tissue cycle AMP could be used as an indicator of physiological stress.

Document Details

Document Type
Technical Report
Publication Date
May 01, 1973
Accession Number
ADA020277

Entities

People

  • B. F. Burgess

Tags

DTIC Thesaurus Topics

  • Acids
  • Alcohols
  • Chemical Compounds
  • Excretion
  • Glycerols
  • Hippuric Acid
  • Indicators
  • Organic Compounds
  • Pilot Studies
  • Stress (Physiology)
  • Sugar Alcohols

Readers

  • Cardiovascular Physiology
  • Theoretical Analysis.