Dopamine Uptake in the Somatic Cell Hybrid NX31

Abstract

The authors have investigated the kinetics and pharmacology of membrane transport of 3,4-dihydroxyphenylethylamine (dopamine) in the neuroblastoma clone N18TG2 and mouse sympathetic ganglion cells. NX31 was grown in exponential growth phase and in the presence of dibutyryl cyclic adenosine monophosphate, a compound known to initiate morphological and biochemical modulation, in order to investigate possible transitions in kinetic properties during differentiation.

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Document Details

Document Type
Technical Report
Publication Date
Aug 01, 1975
Accession Number
ADA020381

Entities

People

  • P. R. Myers
  • W. G. Shain Jr.

Organizations

  • Armed Forces Radiobiology Research Institute

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Acetic Acid
  • Amines
  • Amino Acids
  • Brain
  • Catecholamines
  • Cell Line
  • Cells
  • Chemistry
  • Chromatography
  • Column Chromatography
  • Cultured Cells
  • Kinetics
  • Materials
  • Metabolism
  • Norepinephrine
  • Sodium Compounds
  • Thin Layer Chromatography

Readers

  • Cardiovascular Physiology
  • Molecular and Cellular Biochemistry