Research Report from Military Medicine (Investigations Using Chemical Radioprotective Agents on Mammals),

Abstract

The radioprotective qualities of the compounds WR 2721 (s-2-(3-aminopropylamino) ethylphosphorothioic acid) and WR 2823 (S-2-(3-Aminopropylamino) amylphosphorothioic acid) were tested in female mice. WR 2721 revealed high effectiveness after prophylactic i.p. application, the DRF (dose reduction factor) being 2.4. The prophylactic application of WR 2823, however, resulted in a DRF of 2.0. WR 2721 has also been tested in mice after combined injuries (whole-body irradiation and open skin wound). The radioprotective effect was nearly as good as after irradiation only, the DRF being 2.3. (Author)

Document Details

Document Type
Technical Report
Publication Date
Feb 17, 1976
Accession Number
ADA021715

Entities

People

  • F. Verspohl
  • O. Messerschmidt

Organizations

  • US Army Medical Information and Intelligence Agency

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Germany
  • Health
  • Medical Specialties
  • Military Medicine
  • Radiobiology
  • Radioprotective Agents
  • Sanitation
  • West Germany
  • Whole Body Irradiation

Readers

  • Nuclear and Radiation Engineering.
  • Parasitology and Pharmacology of Malaria.