Hazard Evaluation of Candidate Face Net Impregnant, ENT-80, 4-Biphenylol.

Abstract

A hazard evaluation of the candidate face net impregnant, technical grade 4-biphenylol (ENT-80), was performed by means of laboratory animal studies using rats, rabbits and guinea pigs. The technical grade compound did not produce primary irritation when applied to the intact or abraded skin of rabbits. No corneal injury, iritis or conjunctivitis was observed after a single application of the technical grade compound to the eyes of rabbits. No skin sensitization reaction in guinea pigs or photochemical irritation in rabbits was seen with this compound. Data indicate little acute toxic hazard from accidental ingestion. Acute aerosol, as well as acute and subchronic vapor, inhalation exposures of rats resulted experimentally in no deleterious effect. It is recommended that ENT-80 be approved for testing as a candidate face net impregnant.

Document Details

Document Type
Technical Report
Publication Date
Mar 15, 1976
Accession Number
ADA021990

Entities

People

  • Conrad R. Pope
  • John G. Harvey Jr.
  • Joseph A. Macko Jr.

Organizations

  • United States Army Medical Command

Tags

DTIC Thesaurus Topics

  • Anatomy
  • Animals
  • Biological Sciences
  • Cells (Biology)
  • Conjunctival Diseases
  • Digestive System Processes
  • Eukaryotes
  • Eye Diseases
  • Hazards
  • Impregnation
  • Irritation
  • Laboratory Animals
  • Lagomorphs
  • Rodents
  • Test And Evaluation
  • Toxic Hazards

Fields of Study

  • Medicine

Readers

  • Toxicology/Environmental Toxicology