Retinal Changes Induced by Heavy Particles: A New Therapy Modality

Abstract

The effects of accelerated oxygen nuclei upon the retina of a nonhuman primate have been investigated. This simulated deep space radiation affords the possibility of delivering great quantities of energy (at a predetermined depth) within the eye, while but minimally irradiating interposing tissues. When compared with the clinical results following the use of cobalt plaques the oxygen ion has demonstrated a significant compression of both time and dose in achieving the same degree of tissue effect. Therefore, the possibility obtains for a greater local irradiation of intraocular neoplasta with a sharp reduction of radiation damage to surrounding non-neoplastic ocular tissues.

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Document Details

Document Type
Technical Report
Publication Date
Nov 01, 1975
Accession Number
ADA022449

Entities

People

  • Charles H. Bonney
  • David M. Hunter
  • Jerome H. Krupp
  • John E. Pickering

Organizations

  • United States Air Force School of Aerospace Medicine

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Aerospace Medicine
  • Air Force
  • Air Force Facilities
  • Animals
  • Cosmic Rays
  • Electron Microscopy
  • Energy
  • Eye Diseases
  • Government Procurement
  • Laboratory Animals
  • Medical Personnel
  • Ophthalmology
  • Photographs
  • Radiation
  • Rhesus Monkeys
  • Veins
  • X Rays

Fields of Study

  • Medicine
  • Physics

Readers

  • Oncology and Biomarker-Based Cancer Detection.
  • Pulsed Power and Plasma Physics.
  • Vision Science/Vision Psychology/Cognitive Neuroscience.

Technology Areas

  • Space