Studies on Typhus and Spotted Fever.
Abstract
;Contents: Competitive inhibition by cell membrane fragments of rickettsial uptake by CE cells in suspension; Estimation of absolute number of infectious rickettsiae; Further characterization of growth cycle of Rickettsia prowazeki in CE cell cultures; Growth of R. prowazeki in enucleated cells; Temperature sensitivity of uptake, growth, viability and plaque formation by R. prowazeki; Demonstration of an antigenic slime layer on virulent and attenuated R. prowazeki; Production of suspensions of purified intact R. prowazeki spheroplasts; Lysis of purified spheroplasts under controlled conditions and visualization of genome; Antibiotic resistant mutants of R. prowazeki; Dual infection of CE cells with two strains of R. prowazeki and selective intracellular lysis of one strain through formation of penicillin-induced unstable spheroplasts; Production of plaque-purified seeds of spotted fever group rickettsiae; Studies on the plaques of spotted fever group rickettsiae; In vitro infection cycle of spotted fever group rickettsiae; Ultrastructure of Rickettsia rickettsii; Serological differentiation of field isolates of spotted fever group; Selected references.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jan 01, 1976
- Accession Number
- ADA024545
Entities
People
- Charles L. Wisseman Jr.
Organizations
- University of Maryland, Baltimore