Stored Blood Function.
Abstract
Techniques have been developed to perfuse isolated cow eyes with whole blood at physiological rates of flow and controlled levels of pO2, pCO2, and pH, for extended periods of time (up to 24 hours). This experimental eye model has been designed to study the effects of changes in blood parameters on retinal metabolism and circulation. Using fresh and stored blood alternately to perfuse the isolated eye, the author investigates the influence of red cell affinity for oxygen on the retinal circulation; an increase in red cell affinity, in stored blood, produces a dilation of the retinal arteries.
Document Details
- Document Type
- Technical Report
- Publication Date
- Apr 30, 1976
- Accession Number
- ADA025001
Entities
People
- Marie-anne Castany
Organizations
- Smith-Kettlewell Eye Research Institute