Field Ionization Mass Spectrometric Rapid Diagnosis of Infectious Diseases

Abstract

This report describes the second phase of a research program aimed at the utilization of multicomponent analysis by field ionization mass spectrometry for diagnosis of infectious diseases. During this phase it has been demonstrated that infectious hepatitis can be diagnosed with a high degree of confidence through analysis of the molecular weight profile of the acidic metabolites in urine. New sample preparation techniques, instrumentation, and computerized statistical analysis have been developed during this phase of the program.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 1975
Accession Number
ADA025407

Entities

People

  • Martin E. Scolnick
  • Michael Anbar
  • Robert L. Dyer

Organizations

  • SRI International

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Amino Acids
  • Bacterial Infections
  • Carboxylic Acids
  • Chemical Synthesis
  • Chemistry
  • Computer Programs
  • Diseases And Disorders
  • Gram-Negative Bacterial Infections
  • Health Services
  • Infection
  • Infectious Diseases
  • Mass Spectra
  • Mass Spectrometers
  • Mass Spectrometry
  • Spectrometers
  • Spectrometry
  • Statistical Analysis

Fields of Study

  • Chemistry

Readers

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