Immunology of Schistosomiasis.

Abstract

The original purpose of this contract was to find a process by which tissue surface antigens might be modified or changed. To accomplish this, a model system was needed in which surface antigen modification was known to occur naturally. Such a system was available in a host-parasite model using rodent hosts and the parasitic blood fluke, Schistosoma mansoni. Invading stages of this schistosome cover their surface with host-like antigens and thus protect themselves against destruction by host antibodies.

Document Details

Document Type
Technical Report
Publication Date
Jul 01, 1975
Accession Number
ADA028368

Entities

People

  • M. A. Stirewalt

Tags

DTIC Thesaurus Topics

  • Allergy And Immunology
  • Anatomy
  • Animals
  • Antibodies
  • Antigens
  • Biological Sciences
  • Biology
  • Cells (Biology)
  • Contracts
  • Eukaryotes
  • Helminthiasis
  • Parasites
  • Parasitology
  • Schistosoma
  • Schistosoma Mansoni

Fields of Study

  • Biology
  • Medicine

Readers

  • Immunology
  • Marine Ecological Systems Migration
  • Systems Analysis and Design