Effect of Inflammatory and Noninflammatory Stress on beta-Hydroxybutyrate and Free Fatty Acids in Rat Blood

Abstract

beta-Hydroxybutyrate and free fatty acid concentrations in rat blood were measured during a variety of inflammatory and noninflammatory stresses. Inflammatory stresses included infection with Streptococcus pneumoniae, endotoxemia and induced turpentine abscess. Noninflammatory stresses included fasting plus screen-restraint and fasting plus femoral fracture. Inflammatory stresses caused a marked inhibition of the normal fasting-induced ketosis and a reduction in the level of circulating free fatty acids. Noninflammatory stresses caused no inhibition of the normal fasting-induced ketosis but did cause a reduction in the level of circulating free fatty acids.

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Document Details

Document Type
Technical Report
Publication Date
Jul 15, 1976
Accession Number
ADA028602

Entities

People

  • Harold A. Neufeld
  • Judith A. Pace
  • Mitchell V. Jr Kaminski

Organizations

  • United States Army Medical Research Institute of Infectious Diseases

Tags

DTIC Thesaurus Topics

  • Anesthesia
  • Animals
  • Biomedical Research
  • Blood
  • Body Temperature
  • Endotoxins
  • Fatty Acids
  • Infection
  • Infectious Diseases
  • Inhibition
  • Ketones
  • Laboratory Animals
  • Maryland
  • Plant Exudates
  • United States
  • Wound Infections

Fields of Study

  • Biology
  • Medicine

Readers

  • Cardiovascular Physiology
  • Immunology
  • Military Logistics and Supply Chain Management