Immunity in Chagas' Disease.

Abstract

This is the final report on the immunity in Chagas' disease contract and it summarizes the results of a diversity of studies directed toward understanding the immunology of this dreaded affliction. Among the achievements mentioned are the development of a culture system which provides infective form Trypanosoma cruzi for immunology studies and the use of these infective forms in the development of a sensitive specific, indirect immunofluorescent antibody test for Chagas' disease. Also mentioned are the facts that the cell membranes of live trypomastigotes are not immunoreactive with the humoral immune response of an infected host and that suppression of parasitemias in chronic Chagas' disease is probably a function of the cell immune system of the host. (Author)

Document Details

Document Type
Technical Report
Publication Date
Aug 25, 1976
Accession Number
ADA029228

Entities

People

  • Duell E. Wood

Tags

DTIC Thesaurus Topics

  • Allergy And Immunology
  • Anatomy
  • Antibodies
  • Biological Sciences
  • Cell Membrane
  • Cells
  • Contracts
  • Diseases And Disorders
  • Immune System
  • Immunity
  • Membranes
  • Parasitemias

Fields of Study

  • Biology
  • Medicine

Readers

  • Gulf War Illness and Chronic Multisymptom Illness in Veterans.
  • Immunology
  • Parasitology and Pharmacology of Malaria.