Swine Influenza Virus Vaccine: Potentiation in Rhesus Monkeys of Antibody Responses by a Nuclease Resistant Derivative of Poly I.Poly C
Abstract
Polyriboinosinic-polyribocytidylic acid stabilized with poly-i-lysine and carboxymethylcellulose (poly ICLC) enhances the antibody response in rhesus monkeys immunized with swine influenza virus subunit vaccine. Monkeys given the vaccine-adjuvant combination had earlier and significantly (P < 0.05) higher titers by 14 days.
Document Details
- Document Type
- Technical Report
- Publication Date
- Oct 04, 1976
- Accession Number
- ADA030745
Entities
People
- Duane E. Hilmas
- Edward L. Stephen
- Hilton B. Levy
- Joseph A. Mangiafico
Organizations
- United States Army Medical Research Institute of Infectious Diseases