Effects on Blood Pressure and Heart Rate of Selective Shielding of Midline Trunk Structures in Monkeys Exposed to 1000 Rads 60 Co

Abstract

Blood pressure (BP) and heart rate (HR) were monitored in three groups of shielded, nonperforming monkeys, and one unshielded control during and after exposure to 1000 rads 60 Co at 150 rad/min. A narrow, vertically-oriented lead shield was located over either the dorsal midline (vertebral column) or laterally just to the left or right of midline in the three shielding groups. Purpose was to determine if selective shielding of underlying structures (e.g., spinal cord, autonomic ganglia, heart, spleen, etc.) would alter the postradiation hypotensive response. No differential effects of shielding placement on BP or HR were observed, nor did the shielding groups differ from the unshielded. Absence of radiosensitive target organs implies the hypotensive trigger site is diffuse, for example, the peripheral vasculature.

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Document Details

Document Type
Technical Report
Publication Date
Jun 18, 1976
Accession Number
ADA030820

Entities

People

  • A. Bruner

Organizations

  • Lovelace Foundation

Tags

Communities of Interest

  • Biomedical
  • Weapons Technologies

DTIC Thesaurus Topics

  • Air Force
  • Anesthesia
  • Animals
  • Arteries
  • Blood
  • Carbides
  • Cardiovascular Physiological Phenomena
  • Heart Rate
  • Laboratory Animals
  • Materials
  • Nuclear Weapons
  • Radiation
  • Spinal Cord
  • Spine
  • Tissues
  • Weapons
  • Weapons Effects

Readers

  • Cardiovascular Physiology
  • Neuroscience
  • Nuclear and Radiation Engineering.