Toxic Hazards Research Unit Annual Technical Report: 1976
Abstract
The research programs of the Toxic Hazards Research Unit (THRU) for the period of June 1975 through May 1976 are reviewed in this report. Chronic toxicity experiments were conducted using JP-4, RJ-4 (perhydromethylcyclopentadiene) and RJ-5 (reduced dimers of bicyclopentadiene) jet fuels. Studies were carried out on the oncogenicity of hydrazine, 1,1- dimethylhydrazine and coal tar aerosol. The hepatotoxicity of dimethylnitrosamine was investigated by the oral route and, in conjunction with 1,1-dimethylhydrazine, by the inhalation route. Acute rodent toxicities of hydrogen chloride, hydrogen fluoride and their mixtures with and without alumina dust were determined. The acute effects of tetranitromethane, the isomeric nitrotoluenes and methyl nitrate by various routes of administration were examined. Oral, cutaneous and inhalation toxicity determinations and skin corrosion studies were made on a number of transportable chemical agents.
Document Details
- Document Type
- Technical Report
- Publication Date
- Sep 01, 1976
- Accession Number
- ADA031860
Entities
People
- E. H. Vernot
- J. D. Macewen
Organizations
- University of California, Irvine