Enterotoxigenicity and Invasive Capacity of 'Enteropathogenic' Serotypes of 'Escherichia coli'

Abstract

Forty-two strains of Escherichia coli that agglutinated in pools of antisera used to identify 'enteropathogenic' serotypes were tested for heat- labile and heat-stable toxin production and for their ability to invade intestinal mucosa. None of the strains tested were enterotoxigenic or enteroinvasive as determined by the adrenal cell (heat-labile toxin), the suckling mouse (heat-stable toxin), or guinea pig eye (invasive capacity) assays. Observations suggest that serotyping of E. coli is an unreliable method to identify isolates that are capable of causing gastroenteritis, at least as determined by available in vitro techniques.

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Document Details

Document Type
Technical Report
Publication Date
Jul 01, 1976
Accession Number
ADA032516

Entities

People

  • C. P. Chang
  • David R. Smith
  • Gary L. Anderson
  • Peter D. Echeverria

Organizations

  • Naval Medical Research Center

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Animals
  • Antigens
  • Biological Toxins
  • Biomedical Research
  • Body Weight
  • Cells
  • Children
  • Diarrhea
  • Diseases And Disorders
  • Escherichia
  • Escherichia Coli
  • Health Services
  • Immune Serums
  • Infectious Diseases
  • Intestines
  • Navy
  • Rodents

Fields of Study

  • Biology

Readers

  • Microbial Pathology