The Protective Effect of Melanin against Radiation.

Abstract

Oxidation and reduction of autoxidative dopa-melanin were studied. Reduction with neither ascorbic acid nor sodium dithionite led to any overall increase in the number of 5,6-dihydroxyindole units in the melanin polymer. The melanin was oxidised using repsectivley potassium ferricyanide and ceric sulphate solutions but in neither case was the melanin e.s.r. signal diminished. The interaction of melanin's free radicals with cupric ions was shown not to be chemical in nature. The number of bound cupric ions was determined and the value used to calculate the number of free radicals in autoxidative dopa-melanin.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Oct 01, 1976
Accession Number
ADA033604

Entities

People

  • George A. Swan
  • Patricia A. Baldry

Organizations

  • Newcastle University

Tags

Communities of Interest

  • Energy and Power Technologies

DTIC Thesaurus Topics

  • Acids
  • Amplitude
  • Biological Pigments
  • Buffers (Chemistry)
  • Electron Spin Resonance
  • Electron Transfer
  • Free Radicals
  • Fungi
  • Hydrochloric Acid
  • Hydrogen
  • Hydroxides
  • Resonance
  • Rocket Oxidizers
  • Sodium Hydroxide
  • Spin Resonance
  • Tyrosine
  • Vitamin C

Fields of Study

  • Biology

Readers

  • Analytical Chemistry
  • Electrochemical Engineering/ Fuel Cell Technologies
  • Women's Health and Cancer Risk Research: African American Women and Pregnancy Outcomes.