Pneumococcal Meningitis in a Rhesus Monkey.
Abstract
A recently acquired young, 2.8-kg male rhesus monkey (Macaca mulatta) demonstrated a peculiar behavioral pattern, depression, and anorexia. Approximately 40 hr later, hyperestheisa, generalized muscle tremors, ataxia, and nystagmus became apparent. Cerebrospinal fluid contained numerous gram-positive cocci; subsequently, pure cultures of Streptococcus (Diplococcus) pneumoniae were isolated. Extensive antibiotic and supportive treatment for pneumococcal meningitis was administrated for 12 da. The monkey appeared to respond to treatment, but 9 da following cessation of all treatment, the monkey demonstrated residual central nervous system signs which progressed until the animal was euthanatized 3 wk later. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Dec 17, 1976
- Accession Number
- ADA033823
Entities
People
- Donald G. Harrington
- Gary T. Burger
- Robert L. Hickman
- Roy T. Faulkner
Organizations
- United States Army Medical Research Institute of Infectious Diseases