Resistance of the Opossum (Didelphis Virginiana) to Envenomation by Snakes of the Crotalidae Family.

Abstract

Whether the North American opossum, Dipelphis virginiana, has a natural resistance to envenomation by 12 species of snakes from the families Crotalidae, Viperidae, Elapidae, and Hyprophidae was studied. Challenge of the anesthetized opossum was by actual snakebite or intravenous injection of 4 to 20 times the dose known to be lethal to susceptible mammals. Some animals that survived the snakebite were given venom intravenously 40 to 90 minutes after the bite. Heart and respiratory rate, EKG, and blood pressure were monitored for 2 hours after envenomation, and surviving animals were observed for signs of poisoning for 30 days. The opossum survived the venom of the following snakes of the Crotalidae family: eastern diamondback rattlesnake, western diamondback rattlesnake, copperhead, cottonmouth moccasin, Mexican copperhead, and Central American mossasin. It died when challenged with the venom of the Indian cobra, Chinese cobra, coral snake, cape cobra, puff adder, and sea snake.

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Document Details

Document Type
Technical Report
Publication Date
Dec 01, 1976
Accession Number
ADA034590

Entities

People

  • James A. Vick
  • Robert M. Werner

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Albumins
  • Animals
  • Arteries
  • Bites And Stings
  • Blood
  • Cardiovascular Physiological Phenomena
  • Chemical Warfare Agents
  • Electrocardiography
  • Health Services
  • Heart Rate
  • Laboratory Animals
  • Lethal Dosage
  • New York
  • Physiological Effects
  • Public Health
  • Resistance
  • Respiration Disorders

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