Toxicologic Studies with Didymium Nitrate as Modified by Site of Injection and Whole-Body Radiation,
Abstract
The rare-earth mixture didymium (as the nitrate) was administered to rats intraperitoneally, subcutaneously, and in wound implantation. Mortality and clinical sequelae were observed. When groups of these animals were subjected to 800 r of Co60 gamma irradiation, mortality was increased in all treatment groups. This increase was statistically significant in the intraperitoneal experiment and the COmbined effect appears to be synergistic. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Nov 01, 1958
- Accession Number
- ADA035232
Entities
People
- George S. Melville Jr.
- Quentin L. Hartwig
- Thomas P. Leffingwell