Pulmonary Functions in Conscious and Anesthetized Rhesus Monkeys.

Abstract

Techniques for measurements of selected pulmonary functions in conscious and anesthetized rhesus macaques (Macaca mulatta) are described, and normal baseline values are presented during periods of respiration using pure O2 or room air. Tidal volume, respiratory rate, minute volume, O2 consumption, and specific ventilation were determined hourly for a period of 5 hours in conscious monkeys. Additional variables including dynamic pulmonary compliance, pulmonary resistance, specific compliance, intraesophageal pressure, transpulmonary pressure, inspiratory air flow, expiratory air flow, physiological dead space, CO2, output, respiratory quotient and functional residual capacity, as well as arterial blood pH, PO2, PCO2, HCO3(-), and total CO2 were measured in anesthetized macaques. Further, comparisons of values for certain pulmonary functions were made between this and other studies.

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Document Details

Document Type
Technical Report
Publication Date
Jan 25, 1977
Accession Number
ADA035260

Entities

People

  • Ching-tong Liu
  • Richard D. Delauter

Organizations

  • United States Army Medical Research Institute of Infectious Diseases

Tags

DTIC Thesaurus Topics

  • Air Flow
  • Flow
  • Measurement
  • Monkeys
  • Pulmonary Function
  • Residuals
  • Resistance
  • Respiration
  • Rhesus Monkeys
  • Ventilation

Fields of Study

  • Medicine

Readers

  • Cardiovascular Physiology
  • Toxicology/Environmental Toxicology

Technology Areas

  • Space