Leukocyte Response and Hypoglycemia: Co-Determinants in the Altered Survival to Superlethal Endotoxic Shock.
Abstract
The laboratory has documented a progressively developing hypoglycemia associated with systemic hypotension, hepatosplanchnic pathology and death in endotoxin-shocked dogs. Recent data documented accelerated uptake of glucose in blood following endotoxin, with certain components of the buffy coat responsible for the increased uptake. The present study explored the use of the awake dog as an improved shock model and assayed a possible protective role of leukocytes against the lethal effects of endotoxin.
Document Details
- Document Type
- Technical Report
- Publication Date
- Dec 13, 1976
- Accession Number
- ADA035264
Entities
People
- Beverly K. Beller
- Donald D. Holmes
- Gary L. White
- Lerner B. Hinshaw
- Linda T. Archer
Organizations
- University of Oklahoma Health Sciences Center