Immunologic Aspects of Dental Caries. Meningococcal Polysaccharides,
Abstract
Capsular polysaccharides of serogroups A, B and C of Neisseria meningitidis have been tested for safety and immunogenicity in man. Except for a rare local reaction from highly purified polysaccharides no adverse effects have been noted in millions of adults and children who have been vaccinated. An exception to this statement has been those lots of vaccine used in trials in children in Finland in which newer extraction methods were used. This might be a result of the fact that as standards for endotoxin (Rabbit fever method) have been relaxed to allow more rapid and less costly extractions, an increased number of local reactions have occurred.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jan 01, 1976
- Accession Number
- ADA035662
Entities
People
- Malcolm S. Artenstein
Organizations
- Walter Reed Army Institute of Research