Subacute Toxicity of RDX and TNT in Dogs

Abstract

Dogs given daily dosages of RDX of 0.1, 1 or 10 mg/kg/day for 90 days developed no signs of toxicity other than temporary episodes of emesis to which a tolerance apparently developed. One medium level animal died for reasons unrelated to the study. Dogs given daily dosages of TNT of 0.02, 0.1 or 1 mg/kg/ day for 90 days developed no signs of toxicity other than temporary episodes of emesis to which tolerance apparently developed. Laboratory diagnostic procedures and both gross and microscopic postmortem examinations revealed no important differences from controls.

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Document Details

Document Type
Technical Report
Publication Date
Jul 19, 1974
Accession Number
ADA035717

Entities

People

  • E. R. Hart

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Blood
  • Blood Cells
  • Bone Marrow
  • Cells
  • Cellular Structures
  • Chemistry
  • Erythrocytes
  • Hemorrhage
  • Leukocytes
  • Lymphatic System
  • Lymphocytes
  • Medical Personnel
  • Plastic Explosives
  • Rdx
  • Small Intestine
  • Tissues

Readers

  • Psychometric Testing or Psychological Assessment.
  • Rocket Propulsion.
  • Toxicology/Environmental Toxicology