Acute Effects of Gamma Radiation in Primates

Abstract

One hundred seven Macaca mulatta monkeys were exposed in 16 groups to rapid delivery of Co60 gamma rays at doses at 400 r to 40,000 r. Statistical evaluation of the survival time determination of the LD50/30 dose, clinical observations for a 30-day postirradiation period, and immediate postmortem examinations were performed. These three approaches to the investigation of the mechanism of radiation injury and death in the monkey were evaluated. Each method separated the groups of animals into three distinct and corresponding categories. The clinical and pathologic studies undertaken in this experiment provide further elucidation of the central nervous system, gastrointestinal, and hematopoietic types of radiation death.

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Document Details

Document Type
Technical Report
Publication Date
Apr 01, 1959
Accession Number
ADA036103

Entities

People

  • David R. Rovner
  • Frank A. Brown
  • Loren C. Logie
  • Ralph G. Allen Jr.
  • Stephen G. Wilson Jr

Tags

Communities of Interest

  • Weapons Technologies

DTIC Thesaurus Topics

  • Blood
  • Body Weight
  • Bone Marrow
  • Cardiovascular System
  • Central Nervous System
  • Colon
  • Dose Rate
  • Gamma Rays
  • Gastrointestinal Tract
  • Hemorrhage
  • Lymphatic System
  • Measurement
  • Mucous Membrane
  • Nervous System
  • Small Intestine
  • Thorax
  • Tissues

Readers

  • Nuclear and Radiation Engineering.
  • Systems Analysis and Design
  • Toxicology/Environmental Toxicology