Construction of a Generator for Dry Aerosols,

Abstract

Vaccination by dried antigen aerosols necessitates use of generators for solid particles of controlled size. This should be between 1 and 5 micrometers. In this case, the antigens could reach the lower respiratory passages and instigate local immunity. Production of liquid aerosols at controlled size is well known. On the contrary, it is very difficult to obtain a homogeneous powder and disperse it in aerosol form for inhalation. Phenomena of coalescence and hydration develop and the kinetics of settling are not very reproducible. The apparatus which we have used for the problem in the Microbiology Division seems to respond to the specific criteria that has been established.

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Document Details

Document Type
Technical Report
Publication Date
Feb 22, 1977
Accession Number
ADA036113

Entities

People

  • J.-m. Fournier
  • R. Fontanges

Organizations

  • United States Army Medical Research Institute of Infectious Diseases

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Aerosol Generators
  • Aerosols
  • Biomedical Research
  • Centrifugal Force
  • Construction
  • Dry Materials
  • Electric Current
  • Electric Motors
  • Elements
  • Generators
  • Immunity
  • Infectious Diseases
  • Materials
  • Particle Size
  • Particles
  • Security
  • Vaccination

Readers

  • Aerosol Science/Aerosol Physics
  • Infectious Disease/Epidemiology
  • Systems Analysis and Design

Technology Areas

  • Biotechnology