Response of the Cardiovascular System to Vibration and Combined Stresses
Abstract
Low frequency, sinusoidal accelerations were used to quantify the frequency response of cardiovascular regulation in awake, chronically instrumented canines using pharmacologic blocking agents to delineate the relative contributions of cardiac and peripheral vascular mechanisms required to maintain circulatory integrity during time-dependent acceleration loadings. Cyclic heart rate changes observed in the unblocked animals were almost always the same as those of the sinusoidal acceleration for frequencies up to 0.3 Hz. Preliminary results using pharmacologic blockage indicate that the open loop response of aortic pressure is maximal between 0.04 and 0.06 Hz and that the influence of peripheral mechanisms is evident up to 0.03 Hz.
Document Details
- Document Type
- Technical Report
- Publication Date
- Sep 30, 1976
- Accession Number
- ADA039000
Entities
People
- Charles F. Knapp
Organizations
- University of Kentucky