Endocytosis and Transport in Eucaryotic Cells.

Abstract

The investigations completed concern the following areas of research: (a) characterization of the glucose and amino acid transport systems of mouse and guinea pig macrophages and polymorphonuclear leukocytes. (b) enhancement of glucose transport by macrophages following a phagocytic stimulus or immunologic activation and attempts to define the mechanism responsible for the increased uptake of the sugar. (c) phagocytic and bactericidal activities of mouse peritoneal macrophages before and after activation by immunological and non-immunological means. (d) cell mediated immune phenomena associated with chronic staphylococcal infections of mice. (e) uptake (pinocytosis) of diphtheria toxin and its fragment A moiety by non-phagocytic and phagocytic cells. (f) interaction of diphtheria toxin with normal and transformed mammalian cells in culture.

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Document Details

Document Type
Technical Report
Publication Date
Mar 15, 1977
Accession Number
ADA039012

Entities

People

  • Peter F. Bonventre

Organizations

  • Stellantis North America (formerly Chrysler)

Tags

DTIC Thesaurus Topics

  • Amino Acids
  • Animals
  • Anti-Infective Agents
  • Bacteria
  • Bacterial Infections
  • Blood
  • Cell Physiological Processes
  • Cells
  • Eukaryotes
  • Infection
  • Listeria Monocytogenes
  • Macrophages
  • Polymorphonuclear Leukocytes
  • Resistance
  • Rodents
  • Staphylococcal Infections
  • Staphylococcus Aureus

Fields of Study

  • Biology
  • Medicine

Readers

  • Immunology
  • Immunology and Pathology
  • Molecular and Cellular Biochemistry